V2 av_gene
255,731 rows · 29 columns
| GENEID | TUMOURID | PATIENTID | GENE_DESC | GENE | COUNT_TESTS | COUNT_RESULTS | COUNT_DATE | ALL_TESTSTATUSES | OVERALL_TS | NO_OF_AB_GATS | DNASEQ_GAT | METHYL_GAT | EXP_GAT | COPYNO_GAT | FUS_TRANS_GAT | ABNORMAL_GAT | NO_OF_SEQ_VARS | ALL_SEQ_VARS | SEQ_VAR | DATE_OVERALL_TS | BEST_DATE_SOURCE_OVERALL_TS | MIN_DATE | MAX_DATE | ALL_PRO_IMPS | NO_OF_PRO_IMPS | PRO_IMP | METHODS | LAB_NAME |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 100004880 | 11751574 | 100004880 | EGFR | 24 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2573T>G | c.2573T>G | 2019-08-07 | 2)requesteddate | 2019-08-07 | 2019-08-07 | p.(Leu858Arg) | 1 | p.(Leu858Arg) | Roche COBAS | Nottingham (molecular lab) |
| 100004881 | 11911047 | 100004881 | EGFR | 24 | 1 | 3 | 1 | a:abnormal,a:abnormal,a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 2 | c.2235_2248>AATTC,c.2369C>T | multiple | 2018-05-06 | 3)receiveddate | 2018-05-04 | 2018-05-06 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100004882 | 11609908 | 100004882 | EGFR | 24 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2236_2248delinsATTC | c.2236_2248delinsATTC | 2019-07-31 | 1)authoriseddate | 2019-07-28 | 2019-07-31 | p.L747_T751del | 1 | p.L747_T751del | Roche COBAS | Royal Marsden (molecular lab) |
| 100004883 | 10171907 | 100004883 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-07-28 | 3)receiveddate | 2017-07-29 | 2017-07-28 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004884 | 10453029 | 100004884 | EGFR | 24 | 4 | 4 | 1 | a:abnormal,a:abnormal,b:normal,a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2573T>G | c.2573T>G | 2017-08-27 | 1)authoriseddate | 2017-08-27 | 2017-08-27 | p.Leu858Arg | 1 | p.Leu858Arg | Roche COBAS | Birmingham (molecular lab) |
| 100004885 | 10654608 | 100004885 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-06-11 | 3)receiveddate | 2019-06-06 | 2019-06-11 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100004886 | 10446322 | 100004886 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-04-24 | 3)receiveddate | 2017-04-21 | 2017-04-24 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100004887 | 11703011 | 100004887 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-10-03 | 3)receiveddate | 2017-10-03 | 2017-10-03 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004888 | 11103767 | 100004888 | EGFR | 24 | 1 | 1 | 1 | a:abnormal,a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2582T>A | c.2582T>A | 2019-05-12 | 1)authoriseddate | 2019-05-12 | 2019-05-12 | p.(E746_A750del) | 1 | p.(E746_A750del) | Roche COBAS | Royal Marsden (molecular lab) |
| 100004889 | 11940701 | 100004889 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-08-10 | 3)receiveddate | 2018-08-20 | 2018-08-10 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004890 | 10626177 | 100004890 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-11-27 | 1)authoriseddate | 2017-11-25 | 2017-11-27 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 100004891 | 11763961 | 100004891 | EGFR | 24 | 4 | 4 | 1 | a:abnormal,b:normal,b:normal,b:normal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2239del18 | c.2239del18 | 2019-02-28 | 1)authoriseddate | 2019-02-24 | 2019-02-28 | p.(Leu858Arg) | 1 | p.(Leu858Arg) | Roche COBAS | Royal Marsden (molecular lab) |
| 100004892 | 11135699 | 100004892 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-10-14 | 3)receiveddate | 2016-10-13 | 2016-10-14 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004893 | 10494831 | 100004893 | EGFR | 24 | 1 | 3 | 1 | a:abnormal,a:abnormal,a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2018-11-15 | 3)receiveddate | 2018-11-16 | 2018-11-15 | p.G719X | 1 | p.G719X | Roche COBAS | Birmingham (molecular lab) |
| 100004894 | 10826354 | 100004894 | EGFR | 24 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2573T>G | c.2573T>G | 2018-02-16 | 1)authoriseddate | 2018-02-15 | 2018-02-16 | p.Leu858Arg | 1 | p.Leu858Arg | Roche COBAS | Royal Marsden (molecular lab) |
| 100004895 | 11714094 | 100004895 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-09-24 | 1)authoriseddate | 2016-08-23 | 2016-09-24 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 100004896 | 10203802 | 100004896 | EGFR | 24 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2240_2257del | c.2240_2257del | 2017-01-23 | 1)authoriseddate | 2017-01-22 | 2017-01-23 | p.(Leu747_Lys754del) | 1 | p.(Leu747_Lys754del) | Real-Time / Quantitative PCR (qPCR) | Liverpool (molecular lab) |
| 100004897 | 10645082 | 100004897 | EGFR | 24 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-07-18 | 3)receiveddate | 2016-07-17 | 2016-07-18 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004898 | 10018779 | 100004898 | EGFR | 24 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-11-10 | 3)receiveddate | 2018-11-11 | 2018-11-10 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100004899 | 10492172 | 100004899 | EGFR | 24 | 1 | 1 | 1 | e:failed | e:failed | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-11-17 | 1)authoriseddate | 2017-11-17 | 2017-11-17 | null | 0 | null | Multiple methods | Bristol (molecular lab) |
| 100004900 | 11639843 | 100004900 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-08-01 | 3)receiveddate | 2019-07-31 | 2019-08-02 | null | 0 | null | Roche COBAS | Nottingham (molecular lab) |
| 100004901 | 11354718 | 100004901 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-04-11 | 3)receiveddate | 2017-04-11 | 2017-04-11 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 100004902 | 11323441 | 100004902 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-01-29 | 3)receiveddate | 2018-01-30 | 2018-01-29 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100004903 | 11667741 | 100004903 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-10-09 | 3)receiveddate | 2017-10-10 | 2017-10-09 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004904 | 10651203 | 100004904 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-25 | 1)authoriseddate | 2017-12-26 | 2017-12-25 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004905 | 10408422 | 100004905 | EGFR | 24 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 2 | c.2573T>G,c.2573T>G | multiple | 2017-03-14 | 1)authoriseddate | 2017-03-17 | 2017-03-14 | p.E746_A750del | 1 | p.E746_A750del | Roche COBAS | Manchester (molecular lab) |
| 100004906 | 10423110 | 100004906 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-02-08 | 3)receiveddate | 2019-02-09 | 2019-02-08 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100004907 | 11533333 | 100004907 | EGFR | 24 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2018-09-29 | 3)receiveddate | 2018-09-28 | 2018-09-29 | p.T790M | 1 | p.T790M | Roche COBAS | Birmingham (molecular lab) |
| 100004908 | 10307573 | 100004908 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-01-18 | 3)receiveddate | 2016-12-11 | 2017-01-18 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004909 | 10374048 | 100004909 | EGFR | 24 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-09-04 | 2)requesteddate | 2017-09-07 | 2017-09-04 | null | 0 | null | Roche COBAS | Bristol (molecular lab) |
| 100004910 | 10873054 | 100004910 | EGFR | 24 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2019-12-25 | 3)receiveddate | 2020-01-15 | 2019-12-25 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 100004911 | 11568029 | 100004911 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-05-03 | 2)requesteddate | 2018-05-29 | 2018-05-03 | null | 0 | null | ARMS / Allele-specific PCR | Liverpool (molecular lab) |
| 100004912 | 10891722 | 100004912 | EGFR | 24 | 1 | 3 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-01-12 | 3)receiveddate | 2018-01-13 | 2018-01-12 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 100004913 | 11116911 | 100004913 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-07-27 | 3)receiveddate | 2016-07-27 | 2016-07-27 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004914 | 11286380 | 100004914 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-03-22 | 1)authoriseddate | 2016-03-19 | 2016-03-22 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004915 | 10083770 | 100004915 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-05-06 | 3)receiveddate | 2018-05-08 | 2018-05-06 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100004917 | 11160447 | 100004917 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-03-20 | 3)receiveddate | 2017-03-18 | 2017-03-20 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100004918 | 10937798 | 100004918 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-24 | 3)receiveddate | 2018-10-21 | 2018-10-24 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100004919 | 11313678 | 100004919 | EGFR | 24 | 1 | 3 | 1 | a:abnormal,a:abnormal,b:normal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2573T>G | c.2573T>G | 2017-09-24 | 1)authoriseddate | 2017-09-23 | 2017-09-24 | p.(Leu858Arg) | 1 | p.(Leu858Arg) | Pyrosequencing | Sheffield (molecular lab) |
| 100004920 | 11790533 | 100004920 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-02 | 1)authoriseddate | 2018-08-27 | 2018-10-02 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 100004921 | 11723214 | 100004921 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-03-05 | 2)requesteddate | 2016-04-01 | 2016-03-05 | null | 0 | null | ARMS / Allele-specific PCR | Liverpool (molecular lab) |
| 100004922 | 11210574 | 100004922 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-03-24 | 1)authoriseddate | 2019-04-03 | 2019-03-24 | null | 0 | null | ARMS / Allele-specific PCR | Liverpool (molecular lab) |
| 100004923 | 10112784 | 100004923 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-03-06 | 1)authoriseddate | 2019-03-04 | 2019-03-06 | null | 0 | null | Fragment length analysis | Bristol (molecular lab) |
| 100004924 | 11075012 | 100004924 | EGFR | 24 | 5 | 5 | 5 | b:normal,b:normal,b:normal,e:failed,e:failed | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-06-24 | 1)authoriseddate | 2017-06-25 | 2017-06-26 | null | 0 | null | Roche COBAS | Cambridge (molecular lab) |
| 100004925 | 11329146 | 100004925 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-03-08 | 1)authoriseddate | 2018-03-06 | 2018-03-08 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 100004926 | 11996101 | 100004926 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-08-09 | 1)authoriseddate | 2017-08-10 | 2017-08-09 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Liverpool (molecular lab) |
| 100004927 | 10140740 | 100004927 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-11-30 | 3)receiveddate | 2016-11-29 | 2016-11-30 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100004928 | 11932820 | 100004928 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-12-25 | 4)collecteddate | 2017-01-03 | 2016-12-25 | null | 0 | null | Mass Spectrometry Genotyping / MALDI-TOF | Newcastle (molecular lab) |
| 100004929 | 11551218 | 100004929 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-01-11 | 1)authoriseddate | 2018-01-10 | 2018-01-11 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100004930 | 10949157 | 100004930 | EGFR | 24 | 2 | 2 | 2 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-09-06 | 1)authoriseddate | 2019-09-07 | 2019-09-06 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |