V2 av_gene
255,731 rows · 29 columns
| GENEID | TUMOURID | PATIENTID | GENE_DESC | GENE | COUNT_TESTS | COUNT_RESULTS | COUNT_DATE | ALL_TESTSTATUSES | OVERALL_TS | NO_OF_AB_GATS | DNASEQ_GAT | METHYL_GAT | EXP_GAT | COPYNO_GAT | FUS_TRANS_GAT | ABNORMAL_GAT | NO_OF_SEQ_VARS | ALL_SEQ_VARS | SEQ_VAR | DATE_OVERALL_TS | BEST_DATE_SOURCE_OVERALL_TS | MIN_DATE | MAX_DATE | ALL_PRO_IMPS | NO_OF_PRO_IMPS | PRO_IMP | METHODS | LAB_NAME |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 130018820 | 11616434 | 130018820 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-03-13 | 1)authoriseddate | 2019-03-15 | 2019-03-13 | null | 0 | null | Pyrosequencing | Birmingham (molecular lab) |
| 130079427 | 11616434 | 130018820 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.35G>A | c.35G>A | 2019-03-13 | 1)authoriseddate | 2019-04-09 | 2019-03-13 | p.(Gly12Asp) | 1 | p.(Gly12Asp) | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 200005095 | 11616380 | 200005095 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-06-30 | 1)authoriseddate | 2017-06-23 | 2017-06-30 | null | 0 | null | Sequencing, Next Generation (NGS) | Leeds (molecular lab) |
| 100017659 | 11616372 | 100017659 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2019-11-05 | 1)authoriseddate | 2019-11-05 | 2019-11-05 | null | 0 | null | Immunochemistry | Pathology lab |
| 80021610 | 11616344 | 80071144 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2019-04-23 | null | null | null | null | 0 | null | null | null |
| 130002277 | 11616340 | 130002277 | PMS2 | 3394 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | under_exp | 0 | null | null | 2018-09-03 | 3)receiveddate | 2018-09-05 | 2018-09-09 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130091144 | 11616340 | 130002277 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-03 | 1)authoriseddate | 2018-09-03 | 2018-09-03 | null | 0 | null | Immunochemistry | Manchester (molecular lab) |
| 130063412 | 11616340 | 130002277 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-03 | 1)authoriseddate | 2018-10-03 | 2018-09-03 | null | 0 | null | Immunochemistry | Pathology lab |
| 130150810 | 11616340 | 130002277 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-03 | 3)receiveddate | 2018-10-03 | 2018-09-13 | null | 0 | null | Immunochemistry | Unknown |
| 130033312 | 11616340 | 130002277 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-03 | 1)authoriseddate | 2018-10-03 | 2018-09-03 | null | 0 | null | Immunochemistry | Pathology lab |
| 130165289 | 11616340 | 130002277 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-03 | 1)authoriseddate | 2018-10-03 | 2018-09-03 | null | 0 | null | Immunochemistry | Pathology lab |
| 130115008 | 11616340 | 130002277 | MLH1 | 2744 | 1 | 3 | 1 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 1 | c.790+5G>A | c.790+5G>A | 2018-09-03 | 1)authoriseddate | 2018-10-03 | 2018-09-03 | null | 0 | null | Immunochemistry | Pathology lab |
| 130163307 | 11616340 | 130002277 | MSH2 | 2804 | 2 | 2 | 2 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-03 | 1)authoriseddate | 2018-10-03 | 2020-04-29 | null | 0 | null | Immunochemistry | Leeds (molecular lab) |
| 130156480 | 11616340 | 130002277 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-03 | 1)authoriseddate | 2018-09-28 | 2018-09-03 | null | 0 | null | Immunochemistry | Cambridge (molecular lab) |
| 130160477 | 11616340 | 130002277 | MSH2 | 2804 | 2 | 2 | 2 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-03 | 1)authoriseddate | 2018-10-03 | 2018-09-03 | null | 0 | null | Immunochemistry | Pathology lab |
| 130142717 | 11616340 | 130002277 | MSH6 | 2808 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-03 | 1)authoriseddate | 2018-10-03 | 2018-09-03 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130131262 | 11616340 | 130002277 | MSH6 | 2808 | 2 | 2 | 2 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-03 | 1)authoriseddate | 2018-10-03 | 2018-09-17 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130010586 | 11616317 | 130010586 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-06-02 | 3)receiveddate | 2018-06-04 | 2018-06-02 | null | 0 | null | Immunochemistry | Pathology lab |
| 130041621 | 11616317 | 130010586 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-06-02 | 1)authoriseddate | 2018-06-27 | 2018-07-21 | null | 0 | null | Immunochemistry | Pathology lab |
| 130120033 | 11616317 | 130010586 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-06-02 | 1)authoriseddate | 2018-06-12 | 2018-06-02 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130099425 | 11616317 | 130010586 | MLH1 | 2744 | 2 | 2 | 2 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-06-02 | 1)authoriseddate | 2018-07-01 | 2018-06-02 | null | 0 | null | Immunochemistry | Unknown |
| 130071714 | 11616317 | 130010586 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-06-02 | 1)authoriseddate | 2018-06-06 | 2018-06-02 | null | 0 | null | Immunochemistry | Pathology lab |
| 100032037 | 11616312 | 100032037 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2016-03-03 | 3)receiveddate | 2016-02-29 | 2016-03-17 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130002650 | 11616296 | 130002650 | PMS2 | 3394 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | under_exp | 0 | null | null | 2018-10-30 | 1)authoriseddate | 2018-11-01 | 2018-10-30 | null | 0 | null | Immunochemistry | Unknown |
| 130063785 | 11616296 | 130002650 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-30 | 1)authoriseddate | 2018-10-24 | 2018-10-30 | null | 0 | null | Immunochemistry | Unknown |
| 130091515 | 11616296 | 130002650 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-30 | 1)authoriseddate | 2018-10-27 | 2018-11-25 | null | 0 | null | Immunochemistry | Pathology lab |
| 130033685 | 11616296 | 130002650 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-30 | 1)authoriseddate | 2018-11-25 | 2018-10-30 | null | 0 | null | Immunochemistry | Pathology lab |
| 100043304 | 11616287 | 100043304 | KRAS | 47 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2018-08-22 | 1)authoriseddate | 2018-01-31 | 2018-08-22 | null | 0 | null | Pyrosequencing | null |
| 100033288 | 11616263 | 100033288 | ROS1 | 67 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2017-10-03 | 1)authoriseddate | 2017-10-04 | 2017-10-03 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 230009129 | 11616256 | 230001549 | ALK | 3 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2019-03-15 | null | null | null | null | 0 | null | null | null |
| 230006238 | 11616256 | 230001549 | BRCA1 | 7 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2019-03-10 | 1)authoriseddate | 2019-03-30 | null | null | 0 | null | Sequencing, Next Generation (NGS) | null |
| 230001549 | 11616256 | 230001549 | PMS2 | 3394 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2019-03-10 | 1)authoriseddate | 2019-03-07 | 2019-03-10 | null | 0 | null | Immunochemistry | Pathology lab |
| 130155257 | 11616241 | 130023874 | KIT | 44 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1655_1669del15 | c.1655_1669del15 | 2019-02-23 | null | null | null | p(Trp557Gly) | 1 | p(Trp557Gly) | null | null |
| 130023874 | 11616241 | 130023874 | PIK3CA | 60 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2016-09-28 | null | 2016-02-05 | 2016-09-28 | null | 0 | null | null | null |
| 130083685 | 11616241 | 130023874 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-09-28 | 3)receiveddate | 2016-09-04 | 2016-09-28 | null | 0 | null | Pyrosequencing | Birmingham (molecular lab) |
| 100061995 | 11616240 | 100016552 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-08-30 | 3)receiveddate | 2017-07-23 | 2017-08-30 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100016552 | 11616240 | 100016552 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-08-08 | 1)authoriseddate | 2017-08-13 | 2017-08-08 | null | 0 | null | Multiple methods | Nottingham (molecular lab) |
| 100043126 | 11616234 | 100043126 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-04-29 | 3)receiveddate | 2016-04-26 | 2016-04-29 | null | 0 | null | Pyrosequencing | Newcastle (molecular lab) |
| 130059838 | 11616210 | 130029476 | KIT | 44 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1669_1674delp.(Trp557_Lys558del) | c.1669_1674delp.(Trp557_Lys558del) | 2016-07-02 | null | null | null | p.(Pro551_Val555del) | 1 | p.(Pro551_Val555del) | Multiple methods | null |
| 130129985 | 11616210 | 130029476 | POLE | 5000 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2016-11-01 | 1)authoriseddate | null | null | null | 0 | null | null | Birmingham (molecular lab) |
| 100023554 | 11616182 | 100023554 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-11-28 | 3)receiveddate | 2019-11-29 | 2019-11-28 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100067537 | 11616182 | 100023554 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-11-28 | 1)authoriseddate | 2019-12-26 | 2019-11-28 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 130006418 | 11616180 | 130006418 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-11-01 | 1)authoriseddate | 2017-11-04 | 2017-11-01 | null | 0 | null | Immunochemistry | Pathology lab |
| 130144352 | 11616180 | 130006418 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-11-01 | 1)authoriseddate | 2017-11-04 | 2017-11-01 | null | 0 | null | Pyrosequencing | Cambridge (molecular lab) |
| 130117502 | 11616180 | 130006418 | KRAS | 47 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-11-01 | 1)authoriseddate | 2017-09-21 | 2017-11-01 | null | 0 | null | Sequencing, Next Generation (NGS) | Birmingham (molecular lab) |
| 130133244 | 11616180 | 130006418 | BRAF | 6 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1780G>A | c.1780G>A | 2017-11-01 | 1)authoriseddate | 2017-10-07 | 2017-11-01 | p.(Val600Arg) | 1 | p.(Val600Arg) | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 130067551 | 11616180 | 130006418 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-11-01 | 1)authoriseddate | 2017-09-20 | 2017-11-01 | null | 0 | null | Immunochemistry | Pathology lab |
| 130095272 | 11616180 | 130006418 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-11-01 | 3)receiveddate | 2017-10-24 | 2017-11-01 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130037453 | 11616180 | 130006418 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-11-01 | 1)authoriseddate | 2017-10-04 | 2017-11-01 | null | 0 | null | Unknown | Unknown |
| 100008172 | 11616174 | 100008172 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-05-09 | 1)authoriseddate | 2016-05-11 | 2016-05-09 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |