V2 av_gene
255,731 rows · 29 columns
| GENEID | TUMOURID | PATIENTID | GENE_DESC | GENE | COUNT_TESTS | COUNT_RESULTS | COUNT_DATE | ALL_TESTSTATUSES | OVERALL_TS | NO_OF_AB_GATS | DNASEQ_GAT | METHYL_GAT | EXP_GAT | COPYNO_GAT | FUS_TRANS_GAT | ABNORMAL_GAT | NO_OF_SEQ_VARS | ALL_SEQ_VARS | SEQ_VAR | DATE_OVERALL_TS | BEST_DATE_SOURCE_OVERALL_TS | MIN_DATE | MAX_DATE | ALL_PRO_IMPS | NO_OF_PRO_IMPS | PRO_IMP | METHODS | LAB_NAME |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 130120476 | 11636620 | 130011343 | NRAS | 56 | 1 | 1 | 1 | g:unknown/null | g:unknown/null | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-06-23 | 1)authoriseddate | 2016-06-16 | 2016-06-23 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130100178 | 11636620 | 130011343 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-06-23 | 3)receiveddate | 2016-07-01 | 2016-06-23 | null | 0 | null | Immunochemistry | Unknown |
| 230000473 | 11636592 | 230000473 | PMS2 | 3394 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2019-04-02 | null | null | 2019-04-02 | p.(Arg1190Gln) | 1 | p.(Arg1190Gln) | Immunochemistry | Pathology lab |
| 230009619 | 11636592 | 230000473 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-07-10 | 4)collecteddate | 2018-11-22 | 2019-07-10 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 230007302 | 11636592 | 230000473 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-07-05 | 3)receiveddate | 2019-02-20 | 2019-07-05 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 230003027 | 11636592 | 230000473 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-04-02 | 4)collecteddate | 2018-11-22 | 2019-04-02 | null | 0 | null | Immunochemistry | Pathology lab |
| 230005416 | 11636592 | 230000473 | MSH2 | 2804 | 1 | 1 | 1 | null | g:unknown/null | 2 | a:abnormal_dna_sq | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | multiple | 0 | null | null | 2019-07-05 | 1)authoriseddate | null | 2019-07-05 | null | 0 | null | Immunochemistry | Pathology lab |
| 230008677 | 11636592 | 230000473 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-07-05 | 1)authoriseddate | 2018-12-21 | 2019-07-05 | null | 0 | null | Immunochemistry | Pathology lab |
| 130106549 | 11636572 | 130018241 | KRAS | 47 | 2 | 2 | 2 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.35G>A | c.35G>A | 2018-02-10 | 1)authoriseddate | 2018-03-02 | 2018-02-10 | p.(Gly12Asp) | 1 | p.(Gly12Asp) | Pyrosequencing | Newcastle (molecular lab) |
| 130018241 | 11636572 | 130018241 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-02-10 | 1)authoriseddate | 2018-01-15 | 2018-02-10 | null | 0 | null | Sequencing, Next Generation (NGS) | Leeds (molecular lab) |
| 130049222 | 11636572 | 130018241 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.35G>A | c.35G>A | 2018-02-10 | 3)receiveddate | 2017-12-30 | 2018-03-01 | p.Gly12Asp | 1 | p.Gly12Asp | Pyrosequencing | Birmingham (molecular lab) |
| 130078921 | 11636572 | 130018241 | KRAS | 47 | 2 | 2 | 2 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-02-10 | 3)receiveddate | 2018-02-28 | 2018-02-10 | null | 0 | null | Pyrosequencing | Cambridge (molecular lab) |
| 100012352 | 11636524 | 100012352 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-08-27 | 1)authoriseddate | 2016-08-26 | 2016-08-27 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 130003005 | 11636516 | 130003005 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-01 | 1)authoriseddate | 2017-12-01 | 2017-12-05 | null | 0 | null | Immunochemistry | Pathology lab |
| 130131546 | 11636516 | 130003005 | KRAS | 47 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-02 | 1)authoriseddate | 2017-12-31 | 2017-12-02 | null | 0 | null | Mass Spectrometry Genotyping / MALDI-TOF | Birmingham (molecular lab) |
| 130163576 | 11636516 | 130003005 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.35G>A | c.35G>A | 2017-12-02 | 1)authoriseddate | 2017-12-31 | 2017-12-02 | p.(Gly12Asp) | 1 | p.(Gly12Asp) | Pyrosequencing | Birmingham (molecular lab) |
| 130151084 | 11636516 | 130003005 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-02 | 1)authoriseddate | 2017-12-31 | 2020-06-23 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130034040 | 11636516 | 130003005 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-02 | 3)receiveddate | 2017-12-31 | 2017-12-02 | null | 0 | null | Immunochemistry | Unknown |
| 130166967 | 11636516 | 130003005 | BRAF | 6 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1799T>A | c.1799T>A | 2017-12-02 | 1)authoriseddate | 2017-12-31 | 2017-12-02 | p.V600E | 1 | p.V600E | Roche COBAS | Birmingham (molecular lab) |
| 130115461 | 11636516 | 130003005 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-02 | 1)authoriseddate | 2017-12-24 | 2017-12-02 | null | 0 | null | Immunochemistry | Unknown |
| 130142991 | 11636516 | 130003005 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-02 | 1)authoriseddate | 2017-12-31 | 2017-12-02 | null | 0 | null | Immunochemistry | Pathology lab |
| 130091869 | 11636516 | 130003005 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-02 | 1)authoriseddate | 2017-12-11 | 2019-04-06 | null | 0 | null | Immunochemistry | Pathology lab |
| 130064140 | 11636516 | 130003005 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-02 | 1)authoriseddate | 2017-12-09 | 2017-12-02 | null | 0 | null | Immunochemistry | Pathology lab |
| 130156754 | 11636516 | 130003005 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-02 | 1)authoriseddate | 2017-12-31 | 2017-12-02 | null | 0 | null | Immunochemistry | Unknown |
| 130160750 | 11636516 | 130003005 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.35G>T | c.35G>T | 2017-12-02 | 1)authoriseddate | 2017-12-31 | 2017-12-02 | p.(Gly12Val) | 1 | p.(Gly12Val) | Pyrosequencing | Birmingham (molecular lab) |
| 130165550 | 11636516 | 130003005 | BRAF | 6 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1799T>A | c.1799T>A | 2017-12-02 | 1)authoriseddate | 2017-12-31 | 2017-12-02 | p.(Val600Glu) | 1 | p.(Val600Glu) | Roche COBAS | Nottingham (molecular lab) |
| 100027426 | 11636514 | 100027426 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2016-06-19 | 3)receiveddate | 2016-06-22 | 2016-06-19 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100070483 | 11636514 | 100027426 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-08-07 | 1)authoriseddate | 2016-07-17 | 2016-08-07 | null | 0 | null | Roche COBAS | Manchester (molecular lab) |
| 200005218 | 11636484 | 200005218 | NRAS | 56 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-10-26 | 1)authoriseddate | 2017-11-21 | 2017-10-26 | null | 0 | null | SSCP | Royal Marsden (molecular lab) |
| 100003335 | 11636464 | 100003335 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-11-19 | 3)receiveddate | 2018-11-16 | 2018-11-19 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100090323 | 11636464 | 100003335 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-11-19 | 1)authoriseddate | 2018-11-15 | 2018-11-19 | null | 0 | null | Immunochemistry | Liverpool (molecular lab) |
| 100050094 | 11636464 | 100003335 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-11-19 | 1)authoriseddate | 2018-11-29 | 2018-11-19 | null | 0 | null | Immunochemistry | Liverpool (molecular lab) |
| 200004873 | 11636365 | 200004873 | NRAS | 56 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2017-11-11 | 1)authoriseddate | 2017-10-31 | null | null | 0 | null | Sequencing, Next Generation (NGS) | Leeds (molecular lab) |
| 240000751 | 11636356 | 240000751 | PDGFRA | 59 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-08-17 | 1)authoriseddate | 2019-08-18 | 2019-08-17 | null | 0 | null | FISH - Specific Probe | Manchester (molecular lab) |
| 100018719 | 11636353 | 100018719 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-06-09 | 3)receiveddate | 2018-06-11 | 2018-06-09 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100101159 | 11636353 | 100018719 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-06-09 | 3)receiveddate | 2018-07-01 | 2018-06-09 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100063775 | 11636353 | 100018719 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-06-09 | 3)receiveddate | 2018-06-16 | 2018-06-09 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100064014 | 11636333 | 100019042 | CD274 (PD-L1) | 4842 | 2 | 3 | 2 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-27 | 3)receiveddate | 2019-06-20 | 2019-05-27 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100019042 | 11636333 | 100019042 | CD274 (PD-L1) | 4842 | 2 | 2 | 2 | e:failed,e:failed | e:failed | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-27 | 1)authoriseddate | 2019-05-24 | 2019-06-15 | null | 0 | null | Immunochemistry | Birmingham (molecular lab),Unknown |
| 50017517 | 11636312 | 50129385 | ERBB2 (HER2 / NEU) | 26 | 1 | 1 | 1 | null | g:unknown/null | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | b:normal_copy_no | n:not_applicable_null | null | 0 | null | null | 2017-07-22 | null | null | null | null | 0 | null | null | null |
| 200002993 | 11636307 | 200002993 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-02-11 | 3)receiveddate | 2017-02-27 | 2017-02-11 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 200008894 | 11636307 | 200002993 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-02-11 | 3)receiveddate | 2017-03-07 | 2017-02-11 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 250000424 | 11636271 | 250000424 | ROS1 | 67 | 2 | 2 | 2 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-01-16 | 1)authoriseddate | 2016-03-03 | 2017-01-16 | null | 0 | null | null | Birmingham (molecular lab) |
| 100096200 | 11636257 | 100012721 | ALK | 3 | 3 | 3 | 3 | b:normal,b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-08-10 | 1)authoriseddate | 2018-08-10 | 2018-09-14 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 100012721 | 11636257 | 100012721 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-08-10 | 1)authoriseddate | 2018-08-09 | 2018-08-10 | null | 0 | null | Pyrosequencing | Sheffield (molecular lab) |
| 100058585 | 11636257 | 100012721 | CD274 (PD-L1) | 4842 | 2 | 2 | 1 | e:failed | e:failed | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-08-10 | 3)receiveddate | 2018-08-08 | 2018-08-10 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 240003792 | 11636254 | 240000953 | KIT | 44 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 1 | c.1651_1662del | c.1651_1662del | 2019-07-04 | 3)receiveddate | 2019-07-11 | 2019-07-04 | p.(Glu399del) | 1 | p.(Glu399del) | Sequencing, Next Generation (NGS) | Birmingham (molecular lab) |
| 240000953 | 11636254 | 240000953 | IRF4 | 2267 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2019-07-04 | 2)requesteddate | 2019-07-01 | 2019-07-04 | null | 0 | null | FISH - Specific Probe | Cambridge (molecular lab) |
| 130005170 | 11636225 | 130005170 | PMS2 | 3394 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-06-04 | 1)authoriseddate | 2019-06-06 | 2019-06-04 | null | 0 | null | Immunochemistry | Birmingham (molecular lab),Pathology lab |
| 130094028 | 11636225 | 130005170 | MLH1 | 2744 | 2 | 2 | 2 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-06-04 | 1)authoriseddate | 2019-07-02 | 2019-06-04 | null | 0 | null | Immunochemistry | Pathology lab |