V2 av_gene
255,731 rows · 29 columns
| GENEID | TUMOURID | PATIENTID | GENE_DESC | GENE | COUNT_TESTS | COUNT_RESULTS | COUNT_DATE | ALL_TESTSTATUSES | OVERALL_TS | NO_OF_AB_GATS | DNASEQ_GAT | METHYL_GAT | EXP_GAT | COPYNO_GAT | FUS_TRANS_GAT | ABNORMAL_GAT | NO_OF_SEQ_VARS | ALL_SEQ_VARS | SEQ_VAR | DATE_OVERALL_TS | BEST_DATE_SOURCE_OVERALL_TS | MIN_DATE | MAX_DATE | ALL_PRO_IMPS | NO_OF_PRO_IMPS | PRO_IMP | METHODS | LAB_NAME |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 50023486 | 10067017 | 50083941 | MSH6 | 2808 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2018-05-28 | 3)receiveddate | null | null | p.(Ala146Thr) | 1 | p.(Ala146Thr) | Roche COBAS | Newcastle (molecular lab) |
| 200004972 | 10067005 | 200004972 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-12-17 | null | 2018-12-08 | null | null | 0 | null | null | null |
| 130067529 | 10066983 | 130006396 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-02-14 | 1)authoriseddate | 2017-02-13 | 2017-02-14 | null | 0 | null | Immunochemistry | Pathology lab |
| 130037431 | 10066983 | 130006396 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-02-14 | 1)authoriseddate | 2017-03-03 | 2017-02-14 | null | 0 | null | Immunochemistry | Unknown |
| 130095250 | 10066983 | 130006396 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-02-14 | 3)receiveddate | 2017-01-27 | 2017-02-14 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130006396 | 10066983 | 130006396 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-02-14 | 1)authoriseddate | 2017-02-15 | 2017-02-14 | null | 0 | null | Immunochemistry | Pathology lab |
| 200008097 | 10066968 | 200001283 | BRAF | 6 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1799T>A | c.1799T>A | 2017-05-15 | 1)authoriseddate | 2017-06-13 | 2017-08-12 | p.(Val600Glu) | 1 | p.(Val600Glu) | SSCP | Royal Marsden (molecular lab) |
| 200001283 | 10066968 | 200001283 | BRAF | 6 | 2 | 2 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-05-15 | 3)receiveddate | 2017-05-17 | 2017-05-15 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 130053459 | 10066965 | 130022632 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-29 | 1)authoriseddate | 2018-11-22 | 2018-10-29 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 130082855 | 10066965 | 130022632 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-29 | 1)authoriseddate | 2018-09-12 | 2018-10-29 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 130000076 | 10066906 | 130000076 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-07-22 | 1)authoriseddate | 2019-07-21 | 2019-07-22 | null | 0 | null | Immunochemistry | Pathology lab |
| 100092956 | 10066880 | 100007991 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2017-06-11 | 3)receiveddate | 2017-06-01 | 2017-06-11 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100007991 | 10066880 | 100007991 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-06-04 | 2)requesteddate | 2017-05-31 | 2017-06-04 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 130062653 | 10066879 | 130001518 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-03-02 | 1)authoriseddate | 2016-03-06 | 2016-03-02 | null | 0 | null | Immunochemistry | Pathology lab |
| 130114535 | 10066879 | 130001518 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-03-02 | 1)authoriseddate | 2016-03-16 | 2016-03-02 | null | 0 | null | Immunochemistry | Birmingham (molecular lab),Unknown |
| 130032553 | 10066879 | 130001518 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-03-02 | 1)authoriseddate | 2016-03-11 | 2016-03-02 | null | 0 | null | Immunochemistry | Unknown |
| 130090387 | 10066879 | 130001518 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-03-02 | 1)authoriseddate | 2016-02-02 | 2016-03-02 | null | 0 | null | Immunochemistry | Pathology lab |
| 130001518 | 10066879 | 130001518 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-03-02 | 1)authoriseddate | 2016-03-03 | 2016-03-02 | null | 0 | null | Immunochemistry | Pathology lab |
| 100042396 | 10066843 | 100042396 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-09-24 | null | 2017-10-15 | 2017-09-24 | null | 0 | null | Sequencing, Next Generation (NGS) | Newcastle (molecular lab) |
| 130077232 | 10066819 | 130016349 | MSH6 | 2808 | 1 | 2 | 1 | a:abnormal,a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | under_exp | 0 | null | null | 2018-10-28 | 1)authoriseddate | 2018-11-26 | 2018-10-28 | null | 0 | null | Immunochemistry | Pathology lab |
| 130016349 | 10066819 | 130016349 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-28 | 1)authoriseddate | 2018-11-25 | 2018-10-28 | null | 0 | null | Sequencing, Dideoxy/Sanger | Exeter (molecular lab) |
| 130104935 | 10066819 | 130016349 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-28 | 1)authoriseddate | 2018-11-26 | 2018-10-28 | null | 0 | null | Immunochemistry | Pathology lab |
| 130047356 | 10066819 | 130016349 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.35G>T | c.35G>T | 2018-10-28 | 1)authoriseddate | 2018-11-12 | 2018-10-28 | p.Gly12Val | 1 | p.Gly12Val | Pyrosequencing | Manchester (molecular lab) |
| 100023500 | 10066798 | 100023500 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-03-09 | 3)receiveddate | 2017-03-10 | 2017-03-09 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100048203 | 10066789 | 100001254 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2019-12-15 | 1)authoriseddate | 2020-01-12 | 2019-12-15 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100089057 | 10066789 | 100001254 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2019-12-16 | 3)receiveddate | 2019-12-29 | 2019-12-16 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100001254 | 10066789 | 100001254 | EGFR | 24 | 1 | 3 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-12-15 | 3)receiveddate | 2019-12-13 | 2019-12-15 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Birmingham (molecular lab) |
| 100120681 | 10066789 | 100001254 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_copy_no_gain | b:normal_fusion/trans | null | 0 | null | null | 2019-12-16 | 2)requesteddate | 2020-01-03 | 2019-12-16 | null | 0 | null | FISH - Specific Probe | Cambridge (molecular lab) |
| 100101052 | 10066785 | 100018580 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2016-10-03 | 3)receiveddate | 2016-10-09 | 2016-10-03 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100063662 | 10066785 | 100018580 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-10-03 | 3)receiveddate | 2016-09-25 | 2016-10-03 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100018580 | 10066785 | 100018580 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2016-10-03 | 3)receiveddate | 2016-10-01 | 2016-10-03 | null | 0 | null | Immunochemistry | Pathology lab |
| 130016743 | 10066783 | 130016743 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-19 | 3)receiveddate | 2017-12-19 | 2017-12-19 | null | 0 | null | Pyrosequencing | Birmingham (molecular lab) |
| 130047743 | 10066783 | 130016743 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.35G>C | c.35G>C | 2017-12-19 | 1)authoriseddate | 2016-12-04 | 2017-12-19 | p.(Gly12Ala) | 1 | p.(Gly12Ala) | Pyrosequencing | Birmingham (molecular lab) |
| 130105276 | 10066783 | 130016743 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-19 | 3)receiveddate | 2018-01-07 | 2018-01-18 | null | 0 | null | Immunochemistry | Unknown |
| 130077573 | 10066783 | 130016743 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-19 | 3)receiveddate | 2018-01-03 | 2017-12-19 | null | 0 | null | Immunochemistry | Unknown |
| 100012697 | 10066780 | 100012697 | EGFR | 24 | 1 | 3 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-09-14 | 1)authoriseddate | 2017-09-04 | 2017-09-14 | null | 0 | null | Pyrosequencing | Sheffield (molecular lab) |
| 100058567 | 10066780 | 100012697 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2017-09-14 | 1)authoriseddate | 2017-08-05 | 2017-09-14 | null | 0 | null | Immunochemistry | Pathology lab |
| 130119501 | 10066777 | 130009737 | BRAF | 6 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2017-10-05 | 1)authoriseddate | 2017-10-23 | 2017-10-05 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 130098580 | 10066777 | 130009737 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-10-05 | 1)authoriseddate | 2017-09-30 | 2017-10-05 | null | 0 | null | Immunochemistry | Pathology lab |
| 130070866 | 10066777 | 130009737 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-10-05 | 1)authoriseddate | 2017-10-20 | 2017-10-05 | null | 0 | null | Immunochemistry | Unknown |
| 130040772 | 10066777 | 130009737 | MSH6 | 2808 | 5 | 5 | 5 | a:abnormal,b:normal,b:normal,b:normal,a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | under_exp | 0 | null | null | 2017-10-05 | 3)receiveddate | 2017-09-12 | 2017-10-05 | null | 0 | null | Immunochemistry | Unknown |
| 130009737 | 10066777 | 130009737 | PMS2 | 3394 | 1 | 3 | 1 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-10-05 | 1)authoriseddate | 2017-10-03 | 2017-10-05 | null | 0 | null | Immunochemistry | Pathology lab |
| 30087874 | 10066776 | 30178633 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-03-01 | null | null | null | null | 0 | null | Immunochemistry | Unknown |
| 30136893 | 10066776 | 30178633 | KRAS | 47 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-04-23 | 1)authoriseddate | null | null | null | 0 | null | Mass Spectrometry Genotyping / MALDI-TOF | Leeds (molecular lab) |
| 230009938 | 10066756 | 230001410 | BRCA2 | 8 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2019-08-07 | null | null | null | null | 0 | null | Sequencing, Next Generation (NGS) | null |
| 230009072 | 10066756 | 230001410 | BRCA2 | 8 | 1 | 2 | 1 | a:abnormal,b:normal | a:abnormal | 1 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | aa:abnormal_copy_no_loss | n:not_applicable_null | copy_no_loss | 0 | null | null | 2019-08-07 | null | 2019-08-15 | 2019-08-07 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 10062547 | 10066720 | 10430314 | BRAF | 6 | 1 | 1 | 1 | null | g:unknown/null | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2019-06-16 | null | null | 2019-06-16 | null | 0 | null | Gene Expression testing / RT-PCR | null |
| 10052928 | 10066720 | 10430314 | MSH2 | 2804 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2019-06-16 | null | null | null | null | 0 | null | null | null |
| 130072302 | 10066687 | 130011174 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-07-06 | 1)authoriseddate | 2019-07-03 | 2019-07-06 | null | 0 | null | Immunochemistry | Unknown |
| 130100012 | 10066687 | 130011174 | MLH1 | 2744 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | under_exp | 0 | null | null | 2019-07-06 | 1)authoriseddate | 2019-07-27 | 2019-07-27 | null | 0 | null | Immunochemistry | Cambridge (molecular lab) |