V2 av_gene
255,731 rows · 29 columns
| GENEID | TUMOURID | PATIENTID | GENE_DESC | GENE | COUNT_TESTS | COUNT_RESULTS | COUNT_DATE | ALL_TESTSTATUSES | OVERALL_TS | NO_OF_AB_GATS | DNASEQ_GAT | METHYL_GAT | EXP_GAT | COPYNO_GAT | FUS_TRANS_GAT | ABNORMAL_GAT | NO_OF_SEQ_VARS | ALL_SEQ_VARS | SEQ_VAR | DATE_OVERALL_TS | BEST_DATE_SOURCE_OVERALL_TS | MIN_DATE | MAX_DATE | ALL_PRO_IMPS | NO_OF_PRO_IMPS | PRO_IMP | METHODS | LAB_NAME |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 140038471 | 11716784 | 140005432 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | b:normal | b:normal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2018-05-26 | null | null | null | null | 0 | null | Immunochemistry | null |
| 50023533 | 11716790 | 50085240 | MSH6 | 2808 | 1 | 1 | 1 | null | g:unknown/null | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 1 | c.1799T>A | c.1799T>A | 2018-02-19 | 1)authoriseddate | null | null | p.(Val600Glu) | 1 | p.(Val600Glu) | Roche COBAS | Leeds (molecular lab) |
| 100033417 | 11716807 | 100033417 | ROS1 | 67 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2017-03-23 | 1)authoriseddate | 2017-03-23 | 2017-03-23 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100030681 | 11716818 | 100030681 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-07-15 | 1)authoriseddate | 2016-07-17 | 2016-07-15 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100072978 | 11716818 | 100030681 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-10-13 | 1)authoriseddate | 2016-08-12 | 2016-10-13 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Liverpool (molecular lab) |
| 100151120 | 11716818 | 100030681 | ROS1 | 67 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2016-10-19 | 3)receiveddate | 2016-11-07 | 2016-10-19 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100134292 | 11716818 | 100030681 | ROS1 | 67 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2016-10-19 | 3)receiveddate | 2016-11-12 | 2016-10-19 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100088446 | 11716834 | 100000210 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-05-06 | 1)authoriseddate | 2018-06-04 | 2018-05-06 | null | 0 | null | Immunochemistry | Liverpool (molecular lab) |
| 100047265 | 11716834 | 100000210 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-05-06 | 2)requesteddate | 2018-05-10 | 2018-05-06 | null | 0 | null | FISH - Specific Probe | Sheffield (molecular lab) |
| 100000210 | 11716834 | 100000210 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-05-06 | 3)receiveddate | 2018-05-10 | 2018-05-06 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100120290 | 11716834 | 100000210 | ALK | 3 | 2 | 2 | 2 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-05-06 | 3)receiveddate | 2018-05-13 | 2018-06-03 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100142406 | 11716834 | 100000210 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-05-06 | 1)authoriseddate | 2018-05-11 | 2018-05-06 | null | 0 | null | FISH - Specific Probe | Leeds (molecular lab) |
| 130015105 | 11716835 | 130015105 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-10-01 | 3)receiveddate | 2019-10-09 | 2019-10-07 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130103858 | 11716835 | 130015105 | MSH2 | 2804 | 2 | 2 | 2 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-10-02 | 3)receiveddate | 2019-10-30 | 2019-10-02 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130046140 | 11716835 | 130015105 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.34G>T | c.34G>T | 2019-10-01 | 1)authoriseddate | 2019-10-21 | 2019-10-01 | p.(Gly12Cys) | 1 | p.(Gly12Cys) | Pyrosequencing | Leeds (molecular lab) |
| 130076154 | 11716835 | 130015105 | MSH6 | 2808 | 1 | 1 | 1 | g:unknown/null | g:unknown/null | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-10-01 | 1)authoriseddate | 2019-09-13 | 2019-10-01 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130024535 | 11716891 | 130024535 | PIK3CA | 60 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2017-06-25 | 1)authoriseddate | 2017-06-24 | 2017-06-25 | null | 0 | null | Sequencing, Next Generation (NGS) | null |
| 130148690 | 11716909 | 130022032 | TP53 | 79 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 2 | c.584T>C,c.919+1G>A | multiple | 2019-04-11 | 1)authoriseddate | 2019-02-09 | 2019-04-11 | p.(Arg196Ter) | 1 | p.(Arg196Ter) | null | Royal Marsden (molecular lab) |
| 130082290 | 11716909 | 130022032 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-02-05 | 3)receiveddate | 2018-05-03 | 2019-02-05 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 130052893 | 11716909 | 130022032 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-02-05 | 2)requesteddate | 2018-04-25 | 2019-02-05 | null | 0 | null | Roche COBAS | Exeter (molecular lab) |
| 100079769 | 11716921 | 100037935 | KRAS | 47 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-09-17 | 3)receiveddate | 2019-10-16 | 2019-09-17 | null | 0 | null | Mass Spectrometry Genotyping / MALDI-TOF | Royal Marsden (molecular lab) |
| 200003787 | 11716929 | 200003787 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-07-26 | 3)receiveddate | 2019-07-27 | 2019-07-26 | null | 0 | null | Pyrosequencing | Bristol (molecular lab) |
| 200009268 | 11716929 | 200003787 | BRAF | 6 | 1 | 1 | 1 | a:abnormal | a:abnormal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 1 | c.1799T>A | c.1799T>A | 2019-07-26 | 1)authoriseddate | 2017-01-04 | 2019-07-26 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 100112529 | 11716987 | 100036721 | KRAS | 47 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-01-16 | 1)authoriseddate | 2016-10-22 | 2017-01-16 | null | 0 | null | Other | Manchester (molecular lab) |
| 100136578 | 11716987 | 100036721 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-01-16 | 1)authoriseddate | 2016-03-19 | 2017-01-16 | null | 0 | null | Sequencing, Dideoxy/Sanger | Bristol (molecular lab) |
| 100078565 | 11716987 | 100036721 | ROS1 | 67 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2016-05-18 | 1)authoriseddate | 2016-06-09 | 2016-05-18 | null | 0 | null | FISH - Specific Probe | Manchester (molecular lab) |
| 130025591 | 11716992 | 130025591 | TP53 | 79 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.511G>A | c.511G>A | 2019-07-30 | null | null | 2019-07-30 | p.(Ile843_Asp846del) | 1 | p.(Ile843_Asp846del) | Immunochemistry | Birmingham (molecular lab) |
| 130056335 | 11716992 | 130025591 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-07-30 | 1)authoriseddate | 2019-08-24 | 2019-07-30 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130003636 | 11717010 | 130003636 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-02 | 1)authoriseddate | 2019-05-03 | 2019-05-02 | null | 0 | null | Immunochemistry | Pathology lab |
| 130156937 | 11717010 | 130003636 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.35G>A | c.35G>A | 2019-05-02 | 1)authoriseddate | 2019-06-01 | 2019-05-02 | p.Gly12Asp | 1 | p.Gly12Asp | Pyrosequencing | Manchester (molecular lab) |
| 130115833 | 11717010 | 130003636 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-02 | 1)authoriseddate | 2019-06-01 | 2019-07-27 | null | 0 | null | Immunochemistry | Unknown |
| 130160924 | 11717010 | 130003636 | BRAF | 6 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1799T>A | c.1799T>A | 2019-05-09 | 1)authoriseddate | 2019-06-06 | 2019-05-16 | p.(Val600Glu) | 1 | p.(Val600Glu) | Roche COBAS | Newcastle (molecular lab) |
| 130151272 | 11717010 | 130003636 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.34G>T | c.34G>T | 2019-05-02 | 3)receiveddate | 2019-06-01 | 2019-05-02 | p.Gly12Cys | 1 | p.Gly12Cys | Pyrosequencing | Birmingham (molecular lab) |
| 130092498 | 11717010 | 130003636 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-02 | 3)receiveddate | 2019-05-03 | 2019-05-02 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130034671 | 11717010 | 130003636 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-02 | 1)authoriseddate | 2019-06-01 | 2019-05-02 | null | 0 | null | Immunochemistry | Pathology lab |
| 130143190 | 11717010 | 130003636 | KRAS | 47 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-02 | 1)authoriseddate | 2019-06-01 | 2019-05-02 | null | 0 | null | Pyrosequencing | Birmingham (molecular lab) |
| 130131756 | 11717010 | 130003636 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.34G>A | c.34G>A | 2019-05-02 | 1)authoriseddate | 2019-06-01 | 2019-05-02 | p.Gly12Ser | 1 | p.Gly12Ser | Pyrosequencing | Newcastle (molecular lab) |
| 130163733 | 11717010 | 130003636 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-09 | 1)authoriseddate | 2019-05-11 | 2019-05-09 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 130064771 | 11717010 | 130003636 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-02 | 3)receiveddate | 2019-05-08 | 2019-05-14 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 20156114 | 11717017 | 20217499 | ALK | 3 | 1 | 1 | 1 | null | g:unknown/null | 1 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | ab:abnormal_copy_no_gain | n:not_applicable_null | copy_no_gain | 0 | null | null | 2016-04-23 | 1)authoriseddate | null | null | null | 0 | null | null | Birmingham (molecular lab) |
| 210002248 | 11717035 | 210002248 | ERBB2 (HER2 / NEU) | 26 | 2 | 2 | 1 | b:normal,c:borderline | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_copy_no | n:not_applicable_null | null | 0 | null | null | 2017-02-07 | 3)receiveddate | 2017-02-07 | 2017-02-07 | null | 0 | null | FISH - Specific Probe | null |
| 130014829 | 11717046 | 130014829 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-12-15 | 3)receiveddate | 2019-01-03 | 2018-12-15 | null | 0 | null | Immunochemistry | Unknown |
| 130045864 | 11717046 | 130014829 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.35G>A | c.35G>A | 2018-12-15 | 1)authoriseddate | 2018-07-12 | 2018-12-15 | p.(Gly12Asp) | 1 | p.(Gly12Asp) | Mass Spectrometry Genotyping / MALDI-TOF | Newcastle (molecular lab) |
| 130103607 | 11717046 | 130014829 | MSH2 | 2804 | 3 | 3 | 2 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | ca:borderline_a_under_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-12-15 | 3)receiveddate | 2018-07-11 | 2018-12-15 | p.(Leu270Pro) | 1 | p.(Leu270Pro) | Immunochemistry | Birmingham (molecular lab) |
| 130075903 | 11717046 | 130014829 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-12-15 | 1)authoriseddate | 2018-07-28 | 2018-12-15 | null | 0 | null | Sequencing, Next Generation (NGS) | Birmingham (molecular lab) |
| 130011927 | 11717057 | 130011927 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-04-16 | 3)receiveddate | 2017-04-16 | 2017-04-16 | null | 0 | null | Immunochemistry | Pathology lab |
| 130042962 | 11717057 | 130011927 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-04-16 | 1)authoriseddate | 2017-05-12 | 2017-04-16 | null | 0 | null | Immunochemistry | Pathology lab |
| 130100762 | 11717057 | 130011927 | MLH1 | 2744 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | under_exp | 0 | null | null | 2017-04-16 | 4)collecteddate | 2017-04-08 | 2017-05-09 | null | 0 | null | Immunochemistry | Birmingham (molecular lab),Pathology lab |
| 130073054 | 11717057 | 130011927 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-04-16 | 1)authoriseddate | 2017-05-10 | 2017-04-16 | null | 0 | null | Immunochemistry | Pathology lab |
| 100027051 | 11717074 | 100027051 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-29 | 1)authoriseddate | 2018-10-29 | 2018-10-29 | null | 0 | null | Immunochemistry | Pathology lab |