V2 av_gene
255,731 rows · 29 columns
| GENEID | TUMOURID | PATIENTID | GENE_DESC | GENE | COUNT_TESTS | COUNT_RESULTS | COUNT_DATE | ALL_TESTSTATUSES | OVERALL_TS | NO_OF_AB_GATS | DNASEQ_GAT | METHYL_GAT | EXP_GAT | COPYNO_GAT | FUS_TRANS_GAT | ABNORMAL_GAT | NO_OF_SEQ_VARS | ALL_SEQ_VARS | SEQ_VAR | DATE_OVERALL_TS | BEST_DATE_SOURCE_OVERALL_TS | MIN_DATE | MAX_DATE | ALL_PRO_IMPS | NO_OF_PRO_IMPS | PRO_IMP | METHODS | LAB_NAME |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 100165327 | 11687077 | 100041285 | PIK3CA | 60 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2017-10-03 | 1)authoriseddate | 2017-06-05 | 2017-10-03 | null | 0 | null | Other | Royal Marsden (molecular lab) |
| 100041285 | 11687077 | 100041285 | KRAS | 47 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.182A>T | c.182A>T | 2017-06-16 | 3)receiveddate | 2017-07-03 | 2017-06-16 | p.(Gly12Ala) | 1 | p.(Gly12Ala) | Pyrosequencing | Birmingham (molecular lab) |
| 200002154 | 11687100 | 200002154 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-01-15 | 3)receiveddate | 2016-01-14 | 2016-01-15 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 130007222 | 11687125 | 130007222 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-10-17 | 1)authoriseddate | 2016-10-21 | 2016-10-17 | null | 0 | null | Immunochemistry | Pathology lab |
| 130144630 | 11687125 | 130007222 | NRAS | 56 | 1 | 1 | 1 | g:unknown/null | g:unknown/null | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-10-17 | 1)authoriseddate | 2016-10-20 | 2016-10-17 | null | 0 | null | Pyrosequencing | Nottingham (molecular lab) |
| 130117996 | 11687125 | 130007222 | KRAS | 47 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-10-17 | 1)authoriseddate | 2016-11-14 | 2016-10-17 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130038257 | 11687125 | 130007222 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-10-17 | 1)authoriseddate | 2016-09-28 | 2016-10-17 | null | 0 | null | Immunochemistry | Unknown |
| 130096073 | 11687125 | 130007222 | MLH1 | 2744 | 4 | 4 | 1 | b:normal,b:normal,b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-10-17 | 3)receiveddate | 2016-11-07 | 2016-10-17 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130133701 | 11687125 | 130007222 | BRAF | 6 | 1 | 2 | 1 | a:abnormal,a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2016-10-17 | 1)authoriseddate | 2016-11-01 | 2016-10-17 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 130068354 | 11687125 | 130007222 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2016-10-17 | 1)authoriseddate | 2016-10-14 | 2016-10-17 | p.(Leu911Arg) | 1 | p.(Leu911Arg) | Immunochemistry | Pathology lab |
| 200000741 | 11687137 | 200000741 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-24 | 3)receiveddate | 2018-10-19 | 2018-09-24 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100019355 | 11687154 | 100019355 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-02-21 | 3)receiveddate | 2016-02-20 | 2016-02-21 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100128284 | 11687154 | 100019355 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2017-06-20 | 3)receiveddate | 2017-06-12 | 2017-06-20 | null | 0 | null | Immunochemistry | Unknown |
| 100101550 | 11687154 | 100019355 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-06-11 | 3)receiveddate | 2016-02-19 | 2017-06-11 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100064268 | 11687154 | 100019355 | CD274 (PD-L1) | 4842 | 1 | 3 | 1 | b:normal,b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-06-11 | 3)receiveddate | 2017-06-11 | 2017-06-11 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100147319 | 11687154 | 100019355 | EGFR | 24 | 1 | 2 | 1 | e:failed,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-07-07 | 1)authoriseddate | 2016-10-05 | 2017-07-07 | null | 0 | null | Real-Time / Quantitative PCR (qPCR),Roche COBAS | Manchester (molecular lab) |
| 230003469 | 11687188 | 230000939 | MSH6 | 2808 | 1 | 2 | 1 | a:abnormal,a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | under_exp | 0 | null | null | 2017-09-25 | 4)collecteddate | 2017-10-15 | 2017-10-22 | p.(Gly67Arg) ,p.(Tyr625IlefsTer12) | 2 | multiple | DNA methylation / imprinting / epigenetic analysis,Immunochemistry | Birmingham (molecular lab) |
| 230000939 | 11687188 | 230000939 | BRCA2 | 8 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-09-25 | null | null | 2017-09-25 | null | 0 | null | Pyrosequencing | null |
| 230005809 | 11687188 | 230000939 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-11-09 | 1)authoriseddate | 2017-12-01 | 2017-11-09 | null | 0 | null | Immunochemistry | null |
| 100094118 | 11687218 | 100010324 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2017-02-23 | 3)receiveddate | 2017-02-19 | 2017-02-23 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100010324 | 11687218 | 100010324 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-02-22 | 3)receiveddate | 2017-02-22 | 2017-02-22 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100056430 | 11687218 | 100010324 | CD274 (PD-L1) | 4842 | 2 | 3 | 2 | c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-02-22 | 3)receiveddate | 2017-02-21 | 2017-02-22 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100112738 | 11687225 | 100036957 | KRAS | 47 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-04-20 | 1)authoriseddate | 2019-05-04 | 2019-04-20 | null | 0 | null | Pyrosequencing | Birmingham (molecular lab) |
| 100136784 | 11687225 | 100036957 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-04-20 | 1)authoriseddate | 2019-04-10 | 2019-04-21 | null | 0 | null | Pyrosequencing | Leeds (molecular lab) |
| 100078799 | 11687225 | 100036957 | ROS1 | 67 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2017-11-18 | 1)authoriseddate | 2017-10-17 | 2017-11-18 | null | 0 | null | Sequencing, Next Generation (NGS) | Birmingham (molecular lab) |
| 130077907 | 11687234 | 130017112 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-11-03 | 1)authoriseddate | 2019-12-01 | 2019-11-03 | null | 0 | null | Immunochemistry | Unknown |
| 130048110 | 11687234 | 130017112 | KRAS | 47 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-11-03 | 1)authoriseddate | 2019-11-27 | 2019-11-03 | null | 0 | null | Pyrosequencing | Birmingham (molecular lab) |
| 130017112 | 11687234 | 130017112 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-11-03 | 3)receiveddate | 2019-11-03 | 2019-11-03 | null | 0 | null | Pyrosequencing | Birmingham (molecular lab) |
| 130105610 | 11687234 | 130017112 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-11-03 | 1)authoriseddate | 2019-12-02 | 2019-11-03 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 220000411 | 11687253 | 220000411 | MGMT | 51 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | b:normal_epi | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-11-02 | 3)receiveddate | null | 2018-11-02 | null | 0 | null | DNA methylation / imprinting / epigenetic analysis | Birmingham (molecular lab) |
| 210000027 | 11687276 | 210000027 | ERBB2 (HER2 / NEU) | 26 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_copy_no | n:not_applicable_null | null | 0 | null | null | 2017-11-22 | 3)receiveddate | null | 2017-11-22 | null | 0 | null | FISH - Specific Probe | Birmingham (molecular lab) |
| 100021479 | 11687286 | 100021479 | CD274 (PD-L1) | 4842 | 1 | 2 | 1 | c:borderline,c:borderline | c:borderline | 0 | n:not_applicable_null | n:not_applicable_null | cb:borderline_a_over_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-09-08 | 3)receiveddate | 2017-09-09 | 2017-09-08 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100129428 | 11687286 | 100021479 | EGFR | 24 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2573T>G | c.2573T>G | 2017-09-11 | 1)authoriseddate | 2017-09-11 | 2017-09-11 | p.(Leu858Arg) | 1 | p.(Leu858Arg) | Roche COBAS | Manchester (molecular lab) |
| 100102741 | 11687286 | 100021479 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-09-08 | 3)receiveddate | 2017-09-13 | 2017-09-08 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100065915 | 11687286 | 100021479 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-09-08 | 4)collecteddate | 2017-09-29 | 2017-09-08 | null | 0 | null | Sequencing, Next Generation (NGS) | Sheffield (molecular lab) |
| 130003638 | 11687323 | 130003638 | PMS2 | 3394 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | under_exp | 0 | null | null | 2019-06-10 | 1)authoriseddate | 2019-06-10 | 2019-06-20 | null | 0 | null | Immunochemistry | Unknown |
| 130064773 | 11687323 | 130003638 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-06-10 | 3)receiveddate | 2019-06-25 | 2019-06-10 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 130092500 | 11687323 | 130003638 | MLH1 | 2744 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2019-06-10 | 1)authoriseddate | 2019-07-03 | 2019-06-25 | null | 0 | null | Immunochemistry | Pathology lab |
| 130034673 | 11687323 | 130003638 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-06-10 | 3)receiveddate | 2019-06-07 | 2019-06-10 | null | 0 | null | Immunochemistry | Pathology lab |
| 100004245 | 11687337 | 100004245 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-07-10 | 3)receiveddate | 2018-07-10 | 2018-11-08 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100050919 | 11687337 | 100004245 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-07-10 | 3)receiveddate | 2018-07-07 | 2018-07-10 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100090853 | 11687337 | 100004245 | ALK | 3 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-07-11 | 1)authoriseddate | 2018-07-21 | 2018-07-11 | null | 0 | null | FISH - Specific Probe | Birmingham (molecular lab) |
| 200002224 | 11687400 | 200002224 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-10-20 | 1)authoriseddate | 2016-10-30 | 2016-10-20 | null | 0 | null | Pyrosequencing | Manchester (molecular lab) |
| 100069560 | 11687418 | 100026209 | EGFR | 24 | 1 | 1 | 1 | e:failed | e:failed | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-07-21 | 1)authoriseddate | 2016-07-13 | 2016-07-21 | null | 0 | null | Real-Time / Quantitative PCR (qPCR) | Newcastle (molecular lab) |
| 100106079 | 11687418 | 100026209 | EGFR | 24 | 1 | 1 | 1 | a:abnormal,a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2235_2249del | c.2235_2249del | 2016-07-21 | 3)receiveddate | 2016-07-16 | 2016-07-21 | p.(Gly719Cys),p.G719X,p.S768I | 3 | multiple | Roche COBAS | Birmingham (molecular lab) |
| 100026209 | 11687418 | 100026209 | CD274 (PD-L1) | 4842 | 1 | 2 | 1 | b:normal,c:borderline | b:normal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2016-07-21 | 1)authoriseddate | 2016-07-21 | 2016-07-21 | null | 0 | null | Immunochemistry | Unknown |
| 100103925 | 11687427 | 100023200 | CD274 (PD-L1) | 4842 | 1 | 2 | 1 | e:failed,e:failed | e:failed | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-09-10 | 3)receiveddate | 2016-10-07 | 2016-09-10 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100067254 | 11687427 | 100023200 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-09-10 | 1)authoriseddate | 2016-09-29 | 2016-09-10 | null | 0 | null | Roche COBAS | Birmingham (molecular lab) |
| 100023200 | 11687427 | 100023200 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2016-09-10 | 3)receiveddate | 2016-09-13 | 2016-09-10 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100103205 | 11687510 | 100022156 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2016-06-10 | 1)authoriseddate | 2016-06-14 | 2016-06-10 | null | 0 | null | Immunochemistry | Liverpool (molecular lab),Pathology lab |