V2 av_gene
255,731 rows · 29 columns
| GENEID | TUMOURID | PATIENTID | GENE_DESC | GENE | COUNT_TESTS | COUNT_RESULTS | COUNT_DATE | ALL_TESTSTATUSES | OVERALL_TS | NO_OF_AB_GATS | DNASEQ_GAT | METHYL_GAT | EXP_GAT | COPYNO_GAT | FUS_TRANS_GAT | ABNORMAL_GAT | NO_OF_SEQ_VARS | ALL_SEQ_VARS | SEQ_VAR | DATE_OVERALL_TS | BEST_DATE_SOURCE_OVERALL_TS | MIN_DATE | MAX_DATE | ALL_PRO_IMPS | NO_OF_PRO_IMPS | PRO_IMP | METHODS | LAB_NAME |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 40120569 | 11631278 | 40168320 | EGFR | 24 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2017-12-12 | 3)receiveddate | 2017-11-22 | null | null | 0 | null | Unknown | Birmingham (molecular lab) |
| 220002659 | 11631305 | 220002659 | TERT | 77 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2016-11-13 | 3)receiveddate | 2016-11-28 | null | null | 0 | null | Sequencing, Next Generation (NGS) | Birmingham (molecular lab) |
| 220007161 | 11631305 | 220002659 | TERT | 77 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2016-12-29 | 1)authoriseddate | 2017-01-26 | null | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 220005155 | 11631305 | 220002659 | YAP1 | 4772 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-12-15 | 1)authoriseddate | 2016-12-05 | null | null | 0 | null | FISH - Specific Probe | Leeds (molecular lab) |
| 100032808 | 11631313 | 100032808 | ROS1 | 67 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-05-31 | 1)authoriseddate | 2018-06-29 | 2018-05-31 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 250002869 | 11631327 | 250000229 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2019-07-07 | 3)receiveddate | null | null | null | 0 | null | null | Birmingham (molecular lab) |
| 100043181 | 11631333 | 100043181 | PIK3CA | 60 | 1 | 2 | 1 | a:abnormal,a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2016-04-12 | null | null | 2016-04-12 | null | 0 | null | Sequencing, Next Generation (NGS) | Newcastle (molecular lab) |
| 100141312 | 11631383 | 100045091 | HRAS | 39 | 2 | 2 | 2 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-12-30 | 1)authoriseddate | 2017-01-07 | 2016-12-30 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 100180783 | 11631383 | 100045091 | CCND1 | 13 | 2 | 2 | 2 | e:failed,a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2017-01-17 | 1)authoriseddate | 2017-01-26 | 2017-01-17 | p.Arg87Leu | 1 | p.Arg87Leu | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 100184405 | 11631383 | 100045091 | AKT1 | 2 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2017-01-25 | 1)authoriseddate | 2017-02-02 | 2017-01-25 | null | 0 | null | null | null |
| 100177612 | 11631383 | 100045091 | CDK2 | 17 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-01-17 | 1)authoriseddate | 2017-01-27 | 2017-01-17 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 100166344 | 11631383 | 100045091 | CDK2 | 17 | 1 | 1 | 1 | b:normal | b:normal | 1 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | ab:abnormal_copy_no_gain | n:not_applicable_null | copy_no_gain | 1 | c.179C>A | c.179C>A | 2017-01-17 | 1)authoriseddate | 2017-01-23 | 2017-01-17 | p.Ile63Val | 1 | p.Ile63Val | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 100182950 | 11631383 | 100045091 | CCND1 | 13 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-01-17 | 1)authoriseddate | 2017-02-12 | 2017-01-17 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 100173057 | 11631383 | 100045091 | CCND3 | 15 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-01-17 | 1)authoriseddate | 2017-02-03 | 2017-01-17 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130010136 | 11631402 | 130010136 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-03-28 | 1)authoriseddate | 2019-03-27 | 2019-03-28 | null | 0 | null | Immunochemistry | Unknown |
| 130041171 | 11631402 | 130010136 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-03-28 | 1)authoriseddate | 2019-04-26 | 2019-03-28 | null | 0 | null | Immunochemistry | Unknown |
| 130119751 | 11631402 | 130010136 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-23 | 1)authoriseddate | 2019-05-14 | 2019-05-23 | null | 0 | null | Pyrosequencing | Birmingham (molecular lab) |
| 130098977 | 11631402 | 130010136 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-03-28 | 1)authoriseddate | 2019-04-22 | 2019-03-28 | null | 0 | null | Immunochemistry | Pathology lab |
| 130071264 | 11631402 | 130010136 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-03-28 | 1)authoriseddate | 2019-03-27 | 2019-03-28 | null | 0 | null | Immunochemistry | Unknown |
| 230003284 | 11631434 | 230000744 | MSH6 | 2808 | 1 | 2 | 1 | c:borderline,a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | under_exp | 0 | null | null | 2019-06-17 | 3)receiveddate | 2019-07-10 | 2019-06-17 | null | 0 | null | Immunochemistry | Leeds (molecular lab) |
| 230007509 | 11631434 | 230000744 | MLH1 | 2744 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-07-15 | 4)collecteddate | 2019-08-10 | 2019-07-15 | null | 0 | null | Sequencing, Next Generation (NGS) | Birmingham (molecular lab) |
| 230000744 | 11631434 | 230000744 | PMS2 | 3394 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2019-06-17 | 1)authoriseddate | 2019-06-29 | 2019-06-17 | null | 0 | null | Immunochemistry | Unknown |
| 100068338 | 11631442 | 100024611 | EGFR | 24 | 2 | 2 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-04-18 | 1)authoriseddate | 2017-05-07 | 2017-04-18 | null | 0 | null | Roche COBAS | Sheffield (molecular lab) |
| 100104936 | 11631442 | 100024611 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-04-18 | 1)authoriseddate | 2017-04-21 | 2017-04-18 | null | 0 | null | Roche COBAS | Bristol (molecular lab) |
| 100024611 | 11631442 | 100024611 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2017-04-18 | 3)receiveddate | 2017-04-19 | 2017-04-18 | null | 0 | null | Immunochemistry | Pathology lab |
| 250002002 | 11631471 | 250002002 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-01-09 | null | 2019-01-27 | null | null | 0 | null | Immunochemistry | null |
| 100071019 | 11631476 | 100028122 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-11-01 | 1)authoriseddate | 2017-11-04 | 2017-11-01 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 100028122 | 11631476 | 100028122 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2017-11-01 | 3)receiveddate | 2017-11-04 | 2017-11-01 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 220000594 | 11631485 | 220000594 | MGMT | 51 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | a:abnormal_methyl | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | methyl | 0 | null | null | 2018-04-12 | 2)requesteddate | 2018-04-13 | 2018-04-12 | null | 0 | null | DNA methylation / imprinting / epigenetic analysis | Cambridge (molecular lab) |
| 60042585 | 11631487 | 60108712 | EGFR | 24 | 1 | 1 | 1 | null | g:unknown/null | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2016-09-15 | null | null | null | null | 0 | null | Immunochemistry | Royal Marsden (molecular lab) |
| 100029611 | 11631496 | 100029611 | CD274 (PD-L1) | 4842 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | ab:abnormal_over_exp | n:not_applicable_null | n:not_applicable_null | over_exp | 0 | null | null | 2018-03-01 | 1)authoriseddate | 2018-02-25 | 2018-03-01 | null | 0 | null | Immunochemistry | Unknown |
| 100072151 | 11631496 | 100029611 | EGFR | 24 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-03-01 | 1)authoriseddate | 2018-03-24 | 2018-03-01 | null | 0 | null | Roche COBAS | Royal Marsden (molecular lab) |
| 100114720 | 11631510 | 100039085 | BRAF | 6 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-05-07 | 3)receiveddate | 2017-06-03 | 2017-05-07 | null | 0 | null | Sequencing, Next Generation (NGS) | Bristol (molecular lab) |
| 100080874 | 11631510 | 100039085 | KRAS | 47 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-05-07 | 1)authoriseddate | 2017-05-25 | 2017-05-07 | null | 0 | null | Mass Spectrometry Genotyping / MALDI-TOF | Newcastle (molecular lab) |
| 10053129 | 11631520 | 10435132 | BRAF | 6 | 1 | 1 | 1 | null | g:unknown/null | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2019-08-28 | null | 2019-07-15 | 2019-08-28 | null | 0 | null | Sequencing, Next Generation (NGS) | null |
| 130026678 | 11631551 | 130026678 | TP53 | 79 | 1 | 1 | 1 | a:abnormal,a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.818G>A | c.818G>A | 2019-12-07 | 1)authoriseddate | null | 2019-12-07 | p.(Asn288LysfsTer18) | 1 | p.(Asn288LysfsTer18) | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130057355 | 11631551 | 130026678 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-12-16 | 1)authoriseddate | 2019-12-31 | 2019-12-17 | null | 0 | null | Immunochemistry | Pathology lab |
| 50025999 | 11631594 | 50160722 | MSH2 | 2804 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2019-10-02 | null | 2017-05-15 | 2019-10-02 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 220000066 | 11631615 | 220000066 | MGMT | 51 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | n:not_applicable_null | a:abnormal_methyl | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | methyl | 0 | null | null | 2018-12-17 | 3)receiveddate | 2018-12-17 | 2018-12-17 | null | 0 | null | DNA methylation / imprinting / epigenetic analysis | Manchester (molecular lab) |
| 130057589 | 11631622 | 130026928 | PMS2 | 3394 | 1 | 2 | 1 | b:normal,a:abnormal | a:abnormal | 1 | n:not_applicable_null | n:not_applicable_null | aa:abnormal_under_exp | n:not_applicable_null | n:not_applicable_null | under_exp | 0 | null | null | 2018-02-13 | 1)authoriseddate | 2018-03-02 | 2018-02-13 | null | 0 | null | Immunochemistry | Pathology lab |
| 130026928 | 11631622 | 130026928 | PDGFRA | 59 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.2525A>T | c.2525A>T | 2018-02-10 | 1)authoriseddate | 2018-02-15 | 2018-02-10 | p.(Arg273His) | 1 | p.(Arg273His) | Multiple methods | Royal Marsden (molecular lab) |
| 130129100 | 11631622 | 130026928 | KIT | 44 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1653_1673del | c.1653_1673del | 2019-10-08 | null | null | 2019-10-08 | p.Val559Asp | 1 | p.Val559Asp | null | null |
| 100112289 | 11631623 | 100036447 | ROS1 | 67 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-08-21 | 1)authoriseddate | 2018-09-13 | 2018-08-21 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 100078294 | 11631623 | 100036447 | ROS1 | 67 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_fusion/trans | null | 0 | null | null | 2018-08-13 | 1)authoriseddate | 2018-09-03 | 2018-08-13 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |
| 210000301 | 11631669 | 210000301 | ERBB2 (HER2 / NEU) | 26 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | b:normal_copy_no | n:not_applicable_null | null | 0 | null | null | 2019-04-26 | 1)authoriseddate | 2019-04-23 | 2019-04-26 | null | 0 | null | FISH - Specific Probe | Sheffield (molecular lab) |
| 130023523 | 11631674 | 130023523 | PIK3CA | 60 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2017-03-12 | 1)authoriseddate | null | null | null | 0 | null | Sequencing, Next Generation (NGS) | Birmingham (molecular lab) |
| 130002278 | 11631696 | 130002278 | PMS2 | 3394 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-02-12 | 1)authoriseddate | 2019-02-13 | 2019-02-12 | null | 0 | null | Immunochemistry | Pathology lab |
| 130063413 | 11631696 | 130002278 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-02-12 | 3)receiveddate | 2019-03-04 | 2019-02-12 | null | 0 | null | Immunochemistry | Unknown |
| 130160478 | 11631696 | 130002278 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-02-12 | 1)authoriseddate | 2019-02-13 | 2019-02-12 | null | 0 | null | Immunochemistry | Pathology lab |
| 130131263 | 11631696 | 130002278 | MSH6 | 2808 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-02-12 | 1)authoriseddate | 2019-02-17 | 2019-02-12 | null | 0 | null | Immunochemistry | Birmingham (molecular lab) |