V2 av_gene
255,731 rows · 29 columns
| GENEID | TUMOURID | PATIENTID | GENE_DESC | GENE | COUNT_TESTS | COUNT_RESULTS | COUNT_DATE | ALL_TESTSTATUSES | OVERALL_TS | NO_OF_AB_GATS | DNASEQ_GAT | METHYL_GAT | EXP_GAT | COPYNO_GAT | FUS_TRANS_GAT | ABNORMAL_GAT | NO_OF_SEQ_VARS | ALL_SEQ_VARS | SEQ_VAR | DATE_OVERALL_TS | BEST_DATE_SOURCE_OVERALL_TS | MIN_DATE | MAX_DATE | ALL_PRO_IMPS | NO_OF_PRO_IMPS | PRO_IMP | METHODS | LAB_NAME |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 130106396 | 10937101 | 130018063 | KRAS | 47 | 2 | 2 | 2 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-02-27 | 1)authoriseddate | 2019-03-27 | 2019-02-27 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130108567 | 11552489 | 130021567 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-02 | 2)requesteddate | 2019-05-22 | 2019-05-02 | null | 0 | null | Sequencing, Next Generation (NGS) | Cambridge (molecular lab) |
| 220008587 | 10400927 | 220002368 | TERT | 77 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-12-01 | 1)authoriseddate | null | null | null | 0 | null | Sequencing, Next Generation (NGS) | null |
| 130108572 | 10668152 | 130021575 | NRAS | 56 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-26 | 2)requesteddate | 2019-06-05 | 2019-05-26 | null | 0 | null | Sequencing, Next Generation (NGS) | Bristol (molecular lab) |
| 220008585 | 11392201 | 220002365 | TERT | 77 | 1 | 1 | 1 | null | g:unknown/null | 0 | null | null | null | null | null | null | 0 | null | null | 2018-02-27 | 1)authoriseddate | null | 2018-02-27 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130108577 | 11814533 | 130021586 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-03-14 | 2)requesteddate | 2019-03-06 | 2019-03-14 | null | 0 | null | Sequencing, Next Generation (NGS) | Cambridge (molecular lab) |
| 130108578 | 11223307 | 130021588 | NRAS | 56 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-06-26 | 1)authoriseddate | 2017-07-17 | 2017-06-26 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111337 | 11224310 | 130026391 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-09-11 | 1)authoriseddate | 2019-09-26 | 2019-09-11 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111339 | 11697304 | 130026393 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-05-20 | 1)authoriseddate | 2017-05-17 | 2017-05-20 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111343 | 10149345 | 130026402 | PIK3CA | 60 | 1 | 2 | 1 | a:abnormal,a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1637A>C | c.1637A>C | 2019-07-28 | 1)authoriseddate | 2019-07-27 | 2019-07-28 | p.(Arg88Gln) | 1 | p.(Arg88Gln) | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111344 | 11476264 | 130026404 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-08-14 | 1)authoriseddate | 2017-06-05 | 2017-08-14 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111345 | 10858979 | 130026405 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-11-02 | 1)authoriseddate | 2018-11-23 | 2018-11-02 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111346 | 11596868 | 130026406 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-28 | 1)authoriseddate | 2018-02-16 | 2019-05-28 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111347 | 11468432 | 130026407 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-03-27 | 1)authoriseddate | 2019-04-03 | 2019-03-27 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111348 | 11951836 | 130026408 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-09-08 | 1)authoriseddate | 2018-09-15 | 2018-09-08 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111349 | 11527567 | 130026411 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-08-23 | 1)authoriseddate | 2019-06-06 | 2019-08-23 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111354 | 10117165 | 130026417 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-07-11 | 1)authoriseddate | 2017-09-28 | 2018-07-25 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111356 | 11162140 | 130026420 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-06-09 | 1)authoriseddate | 2019-05-19 | 2019-06-09 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111358 | 10532868 | 130026422 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-06-06 | 1)authoriseddate | 2019-05-09 | 2019-06-06 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111360 | 10528495 | 130026425 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-12-03 | 1)authoriseddate | 2018-10-17 | 2019-02-19 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111361 | 10559567 | 130026430 | PIK3CA | 60 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1633G>A | c.1633G>A | 2017-11-26 | 1)authoriseddate | 2017-07-24 | 2017-11-26 | p.(Glu545Lys) | 1 | p.(Glu545Lys) | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111364 | 11295658 | 130026434 | PIK3CA | 60 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.3140A>T | c.3140A>T | 2016-12-09 | 1)authoriseddate | 2017-01-03 | 2016-12-09 | p.(Arg88Gln) | 1 | p.(Arg88Gln) | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111365 | 10464841 | 130026435 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-10-14 | 1)authoriseddate | 2017-11-04 | 2017-10-14 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111367 | 10230324 | 130026440 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-05-17 | 1)authoriseddate | 2017-08-13 | 2019-05-17 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111368 | 11772786 | 130026441 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-03-08 | 1)authoriseddate | 2019-06-03 | 2019-03-08 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111369 | 11907923 | 130026442 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-05-28 | 1)authoriseddate | 2018-06-19 | 2018-05-28 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111371 | 11702129 | 130026445 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-06-10 | 1)authoriseddate | 2019-07-02 | 2019-06-10 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111373 | 11835444 | 130026448 | PIK3CA | 60 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1633G>A | c.1633G>A | 2017-03-21 | 1)authoriseddate | 2017-03-11 | 2017-03-21 | p.(Glu545Lys) | 1 | p.(Glu545Lys) | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111374 | 10048198 | 130026451 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-10-29 | 1)authoriseddate | 2018-10-02 | 2018-10-29 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111376 | 11351315 | 130026453 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-10-25 | 1)authoriseddate | 2017-10-09 | 2017-10-25 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111378 | 10721977 | 130026456 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-08-23 | 1)authoriseddate | 2016-07-02 | 2016-08-23 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111380 | 10332810 | 130026461 | PIK3CA | 60 | 1 | 1 | 1 | e:failed | e:failed | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-06-06 | 1)authoriseddate | 2019-05-29 | 2019-06-06 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111384 | 10525563 | 130026465 | PIK3CA | 60 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.1624G>A | c.1624G>A | 2019-12-10 | 1)authoriseddate | 2020-01-01 | 2019-12-10 | p.(Glu542Lys) | 1 | p.(Glu542Lys) | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111385 | 11663768 | 130026466 | PIK3CA | 60 | 1 | 1 | 1 | a:abnormal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 1 | c.677G>A | c.677G>A | 2018-10-25 | 1)authoriseddate | 2018-11-20 | 2018-10-25 | p.(Arg88Gln) | 1 | p.(Arg88Gln) | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111386 | 11018162 | 130026469 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-01-31 | 1)authoriseddate | 2019-01-12 | 2019-01-31 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111387 | 10353449 | 130026470 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-12-11 | 1)authoriseddate | 2020-01-08 | 2019-12-11 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111389 | 11668953 | 130026472 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-02-01 | 1)authoriseddate | 2019-01-18 | 2019-02-03 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111392 | 10618092 | 130026477 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-04-27 | 1)authoriseddate | 2018-04-16 | 2018-04-27 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111396 | 10000882 | 130026484 | PIK3CA | 60 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-01-06 | 1)authoriseddate | 2016-12-29 | 2017-01-06 | null | 0 | null | Sequencing, Next Generation (NGS) | Royal Marsden (molecular lab) |
| 130111400 | 11998498 | 130026490 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-01-17 | 1)authoriseddate | 2017-01-31 | 2017-01-17 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111405 | 10365563 | 130026498 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-06-15 | 1)authoriseddate | 2018-07-14 | 2018-09-04 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111407 | 11553904 | 130026501 | PIK3CA | 60 | 1 | 1 | 1 | e:failed | e:failed | 0 | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-12-18 | 1)authoriseddate | 2019-12-28 | 2019-12-18 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111409 | 10913306 | 130026503 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-01-06 | 1)authoriseddate | 2016-12-16 | 2017-01-06 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111410 | 11537178 | 130026504 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2018-01-12 | 1)authoriseddate | 2018-02-03 | 2018-01-12 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111411 | 10889541 | 130026505 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2016-12-10 | 1)authoriseddate | 2016-08-13 | 2016-12-10 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111412 | 11832072 | 130026507 | PIK3CA | 60 | 1 | 2 | 1 | b:normal,b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-06-29 | 1)authoriseddate | 2019-05-28 | 2019-06-29 | null | 0 | null | Sequencing, Next Generation (NGS) | Birmingham (molecular lab) |
| 130111413 | 11329862 | 130026509 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2017-09-11 | 1)authoriseddate | 2017-05-24 | 2017-09-11 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111416 | 11029735 | 130026512 | PIK3CA | 60 | 1 | 3 | 1 | a:abnormal,b:normal,b:normal | a:abnormal | 1 | a:abnormal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | dna_sq | 0 | null | null | 2019-08-05 | 1)authoriseddate | 2019-07-29 | 2019-08-05 | p.(Arg93Gln) | 1 | p.(Arg93Gln) | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130111417 | 11905876 | 130026514 | PIK3CA | 60 | 1 | 1 | 1 | b:normal | b:normal | 0 | b:normal_dna_sq | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-10-06 | 1)authoriseddate | 2019-10-15 | 2019-10-06 | null | 0 | null | Sequencing, Next Generation (NGS) | Manchester (molecular lab) |
| 130066129 | 11962358 | 130004996 | MSH2 | 2804 | 1 | 1 | 1 | b:normal | b:normal | 0 | n:not_applicable_null | n:not_applicable_null | b:normal_exp | n:not_applicable_null | n:not_applicable_null | null | 0 | null | null | 2019-02-21 | 1)authoriseddate | 2019-02-25 | 2019-02-21 | null | 0 | null | Sequencing, Next Generation (NGS) | Birmingham (molecular lab) |